| | | Saturday, May 21st, 2022 | | Signed LF Mark Haney to a 4-year contract extension worth a total of $21,988,000. |
| Wednesday, April 27th, 2022 | | Signed C Dan Gilmore to a 3-year contract extension worth a total of $10,800,000. |
| Wednesday, December 15th, 2021 | | Signed free agent C Sergio Guzmán to a 2-year contract worth a total of $4,220,000. | | Placed C Sergio Guzmán on the active roster. | | Placed SS Michael Jones on the active roster. |
| Sunday, December 5th, 2021 | | Signed free agent SS Michael Jones to a 2-year contract worth a total of $3,140,000. |
| Sunday, November 28th, 2021 | | 2B Paul Rose received a 1-year contract through automatic renewal worth a total of $410,000. | | RF Sloan Richardson received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Anthony Green received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Norogumi Kono received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Scott Morgan received a 1-year contract through automatic renewal worth a total of $400,000. | | CF Lance Stanley III received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Tom Clifton received a 1-year contract through automatic renewal worth a total of $410,000. | | MR David Lowery received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Jorge Ramírez received a 1-year contract through automatic renewal worth a total of $400,000. | | C Sandro García received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Ross Brooks received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Greg Davis received a 1-year contract through automatic renewal worth a total of $400,000. | | RF Michael Ellis received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Dante Dawson received a 1-year contract through automatic renewal worth a total of $400,000. | | C Jim Nolan becomes a free-agent. |
| Thursday, November 25th, 2021 | | LF Pepe Lopez received a 1-year contract through arbitration worth a total of $600,000. | | 2B Pedro Rodríguez received a 1-year contract through arbitration worth a total of $800,000. | | MR Timothy Pryor received a 1-year contract through arbitration worth a total of $600,000. |
| Friday, November 5th, 2021 | | Signed LF Tony Aguilar to a 5-year contract extension worth a total of $69,500,000. |
| Tuesday, October 26th, 2021 | | Placed SS Roberto Torres on the 14-day disabled list. | | Placed LF Mark Haney on the active roster. | | Activated LF Mark Haney from the disabled list. |
| Wednesday, October 6th, 2021 | | Placed LF Mark Haney on the 14-day disabled list. | | Purchased the contract of LF Pepe Lopez from Triple A Frisco. |
| Friday, August 20th, 2021 | | Signed CL Orlando Medina to a 3-year contract extension worth a total of $18,900,000. |
| Saturday, August 14th, 2021 | | Signed James Rice to a minor league contract with a signing bonus of $450,000. |
| Monday, August 9th, 2021 | | 1B Bryan Duncan was designated for assignment and placed on waivers. | | Placed SS Roberto Torres on the active roster. |
| Sunday, July 18th, 2021 | | Signed CL Juan Rivera to a 3-year contract extension worth a total of $25,200,000. |
| Wednesday, June 30th, 2021 | | Signed Elvis Barry to a minor league contract with a signing bonus of $170,000. |
| Tuesday, June 29th, 2021 | | Signed Kevin Rogers to a minor league contract with a signing bonus of $500,000. |
| Sunday, June 27th, 2021 | | Signed Kerry Page to a minor league contract with a signing bonus of $1,110,000. | | Signed Eric Guy to a minor league contract with a signing bonus of $180,000. |
| Friday, June 25th, 2021 | | Signed Michael McBride to a minor league contract with a signing bonus of $4,160,000. |
| Saturday, May 1st, 2021 | | Signed 2B Darren Carr to a 1-year contract extension worth a total of $1,200,000. |
| Saturday, April 24th, 2021 | | Signed MR Michael O'Brien to a 2-year contract extension worth a total of $6,800,000. |
| Monday, March 15th, 2021 | | Placed SP Carroll Dixon on the active roster. |
| Saturday, February 20th, 2021 | | Signed free agent SP Carroll Dixon to a 1-year contract worth a total of $1,060,000. |
| Sunday, November 29th, 2020 | | MR Matt Blackett becomes a free-agent. | | SP Anthony Green received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Montelle James received a 1-year contract through automatic renewal worth a total of $400,000. | | 3B Manuel Zambrano received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Shannon Lewis becomes a free-agent. | | MR David Lowery received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Jorge Ramírez received a 1-year contract through automatic renewal worth a total of $400,000. | | LF Pepe Lopez received a 1-year contract through automatic renewal worth a total of $410,000. | | SP Danny Beck becomes a free-agent. | | MR Timothy Pryor received a 1-year contract through automatic renewal worth a total of $410,000. | | SP Greg Davis received a 1-year contract through automatic renewal worth a total of $400,000. | | 1B Jack Shannon becomes a free-agent. | | RF Michael Ellis received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Dante Dawson received a 1-year contract through automatic renewal worth a total of $400,000. | | C Dave Lacy becomes a free-agent. |
| Thursday, November 26th, 2020 | | SP Michael O'Brien received a 1-year contract through arbitration worth a total of $3,600,000. | | 2B Darren Carr received a 1-year contract through arbitration worth a total of $1,169,000. | | LF Tony Aguilar received a 1-year contract through arbitration worth a total of $3,900,000. | | MR Jim Austin becomes a free-agent. | | SP Wesley Manning received a 1-year contract through arbitration worth a total of $624,000. | | MR Bob Johnson received a 1-year contract through arbitration worth a total of $600,000. |
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