| | | Tuesday, May 17th, 2022 | | Signed free agent SP Brett Hawkins to a 1-year contract worth a total of $760,000. |
| Tuesday, May 10th, 2022 | | Signed free agent 1B Ryan Christian to a 1-year contract worth a total of $400,000. |
| Tuesday, May 3rd, 2022 | | Signed free agent 3B Armando Sanchez to a 2-year contract worth a total of $4,000,000. |
| Friday, April 8th, 2022 | | Signed SS Carlos Sánchez to a minor league contract extension. | | Signed C Keith Stokes to a 1-year contract extension worth a total of $1,300,000. | | Signed 1B Ralph Marshall to a minor league contract extension. | | Signed RF Ambrose Bates to a minor league contract extension. | | Signed LF Elwood Perkins to a minor league contract extension. | | Signed C Brian Dodson to a minor league contract extension. |
| Thursday, April 7th, 2022 | | Signed C Bill Dyer to a 1-year contract extension worth a total of $840,000. |
| Wednesday, April 6th, 2022 | | Signed C Victor Stark to a 1-year contract extension worth a total of $860,000. |
| Tuesday, April 5th, 2022 | | Signed RF Gabriel Ortega to a minor league contract extension. |
| Thursday, March 31st, 2022 | | Signed free agent MR Dean Stewart to a 1-year contract worth a total of $4,170,000. |
| Tuesday, March 22nd, 2022 | | Signed MR Bob Detty to a 6-year contract extension worth a total of $37,500,000. | | Signed RF Juan Torres to a minor league contract extension. | | Signed C Miguel Romero to a minor league contract extension. |
| Wednesday, February 2nd, 2022 | | Signed LF Carlos Molina to a 5-year contract extension worth a total of $141,200,000. |
| Wednesday, January 5th, 2022 | | Signed free agent MR Travis Baker to a minor league contract. |
| Saturday, January 1st, 2022 | | Signed free agent SP Owen Stuart to a 2-year contract worth a total of $1,350,000. |
| Thursday, December 30th, 2021 | | Signed free agent SP Jerome Jones to a minor league contract. | | Signed free agent SP Cesar Cruz to a minor league contract. |
| Wednesday, December 29th, 2021 | | Signed free agent SP James Roberts to a minor league contract. | | Signed free agent SP Ed Gorman to a minor league contract. |
| Monday, December 27th, 2021 | | Signed free agent SP Wesley Manning to a minor league contract. |
| Thursday, November 25th, 2021 | | MR Bob Detty received a 1-year contract through arbitration worth a total of $3,270,500. | | RF Matthew Brown received a 1-year contract through arbitration worth a total of $12,500,000. | | CF Bernardo Martinez received a 1-year contract through arbitration worth a total of $2,460,000. | | SS Joaquin Pena received a 1-year contract through arbitration worth a total of $903,000. | | C Keith Stokes received a 1-year contract through arbitration worth a total of $1,200,000. | | LF Todd Jewell received a 1-year contract through arbitration worth a total of $2,800,000. | | DH Barry Benson received a 1-year contract through arbitration worth a total of $3,000,000. | | RF Lonnie Williams received a 1-year contract through arbitration worth a total of $1,000,000. | | 2B Mathew Dupree received a 1-year contract through arbitration worth a total of $1,500,000. |
| Tuesday, November 9th, 2021 | | Signed CF Artie Tidwell to a minor league contract extension. |
| Saturday, August 14th, 2021 | | Failed to sign 5th round draft pick Dan Abbott. |
| Thursday, August 12th, 2021 | | Signed Colt Boggs to a minor league contract with a signing bonus of $250,000. |
| Monday, August 9th, 2021 | | Placed 3B Danny Sydney on the SIMBL Rookie League 7-day disabled list. | | Placed CF Lester Rivers on the SIMBL Rookie League 7-day disabled list. | | Placed 3B Danny Sydney on the SIMBL Rookie League 7-day disabled list. | | Placed CF Lester Rivers on the SIMBL Rookie League 7-day disabled list. |
| Saturday, July 24th, 2021 | | Signed SP Mark Peterson to a minor league contract extension. | | Signed MR Logan Hicks to a minor league contract extension. |
| Friday, July 23rd, 2021 | | Signed SP Tony Mendoza to a minor league contract extension. |
| Tuesday, July 20th, 2021 | | Signed free agent 1B Carlos Rojas to a minor league contract. |
| Sunday, July 11th, 2021 | | Signed Lester Rivers to a minor league contract with a signing bonus of $240,000. |
| Friday, July 9th, 2021 | | Signed Todd Newell to a minor league contract with a signing bonus of $300,000. |
| Tuesday, June 15th, 2021 | | Drafted MR Todd Newell in the 2021 first-year player draft (Round 2, Pick 24, 66th overall pick). | | Drafted CF Lester Rivers in the 2021 first-year player draft (Round 3, Pick 27, 93rd overall pick). | | Drafted 2B Colt Boggs in the 2021 first-year player draft (Round 4, Pick 32, 128th overall pick). | | Drafted RF Dan Abbott in the 2021 first-year player draft (Round 5, Pick 34, 163rd overall pick). | | Drafted SP John Howard in the 2021 first-year player draft (Round 6, Pick 24, 188th overall pick). | | Drafted SS Steve Price in the 2021 first-year player draft (Round 7, Pick 24, 212nd overall pick). | | Drafted SP Geoff Graham in the 2021 first-year player draft (Round 8, Pick 24, 236th overall pick). | | Drafted LF Dan Burton in the 2021 first-year player draft (Round 9, Pick 24, 260th overall pick). | | Drafted SP Bartolo Ramírez in the 2021 first-year player draft (Round 10, Pick 24, 284th overall pick). |
| Monday, June 7th, 2021 | | Placed SP Craig Byrd on the 14-day disabled list. |
| Tuesday, May 4th, 2021 | | Signed free agent CF Artie Tidwell to a minor league contract. |
| Tuesday, April 27th, 2021 | | Signed 1B Colt McAlister to a 8-year contract extension worth a total of $99,800,000. |
| Thursday, April 22nd, 2021 | | Signed SP Vinny Corleone to a 4-year contract extension worth a total of $105,800,000. |
| Tuesday, April 20th, 2021 | | Signed free agent RF Daniel Finley to a minor league contract. | | Signed free agent 2B Arturo Núñez to a minor league contract. |
| Thursday, April 8th, 2021 | | Signed SP Scott Brewer to a 2-year contract extension worth a total of $15,100,000. |
| Saturday, April 3rd, 2021 | | Signed MR Jonathan Coleman to a 3-year contract extension worth a total of $9,600,000. |
| Thursday, February 18th, 2021 | | Signed free agent SS Ken Hill to a minor league contract. |
| Tuesday, February 16th, 2021 | | Signed 3B Steve Waddell to a 2-year contract extension worth a total of $6,800,000. |
| Sunday, November 29th, 2020 | | 1B Colt McAlister received a 1-year contract through automatic renewal worth a total of $410,000. | | RF Matthew Brown received a 1-year contract through automatic renewal worth a total of $410,000. | | CF Bernardo Martinez received a 1-year contract through automatic renewal worth a total of $410,000. | | SS Joaquin Pena received a 1-year contract through automatic renewal worth a total of $410,000. | | DH Todd Jewell received a 1-year contract through automatic renewal worth a total of $410,000. | | SS Tracy Thompson received a 1-year contract through automatic renewal worth a total of $400,000. | | SP Torazo Kumatani becomes a free-agent. | | MR John Perry becomes a free-agent. | | SS Minoru Ine becomes a free-agent. | | SP Manuel Aguirre becomes a free-agent. | | SP Rafael Bonner becomes a free-agent. | | C Kagehisa Uenohara becomes a free-agent. | | SP Jorge Rodríguez becomes a free-agent. |
| Thursday, November 26th, 2020 | | MR Bob Detty received a 1-year contract through arbitration worth a total of $3,000,000. | | 3B Steve Waddell received a 1-year contract through arbitration worth a total of $3,200,000. | | C Keith Stokes received a 1-year contract through arbitration worth a total of $1,100,000. | | MR Jonathan Coleman received a 1-year contract through arbitration worth a total of $3,000,000. | | SP Scott Brewer received a 1-year contract through arbitration worth a total of $4,500,000. | | RF Lonnie Williams received a 1-year contract through arbitration worth a total of $950,000. | | 2B Mathew Dupree received a 1-year contract through arbitration worth a total of $1,400,000. | | MR Chet Wright received a 1-year contract through arbitration worth a total of $800,000. | | SS Rafael Martínez received a 1-year contract through arbitration worth a total of $600,000. |
| Monday, November 9th, 2020 | | Executed the last optional contract year of 2B Michael Turner. |
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