| | | Thursday, May 12th, 2022 | | Signed SS Tyson Chapman to a 2-year contract extension worth a total of $7,680,000. |
| Monday, April 25th, 2022 | | Placed RF Freddie Young on the 14-day disabled list. | | Placed LF Tom Dares on the active roster. |
| Monday, April 18th, 2022 | | LF Tom Dares was designated for assignment and placed on waivers. |
| Monday, April 4th, 2022 | | Signed CF Ray Long to a 3-year contract extension worth a total of $24,400,000. |
| Thursday, March 10th, 2022 | | Signed CL Ron Orr to a 2-year contract extension worth a total of $16,000,000. |
| Sunday, March 6th, 2022 | | Signed 1B Tony Hudson to a 1-year contract extension worth a total of $1,100,000. |
| Sunday, November 28th, 2021 | | 3B Curtis Downing received a 1-year contract through automatic renewal worth a total of $400,000. | | C Rolland Minor becomes a free-agent. | | 3B Dale Hayes becomes a free-agent. | | 1B William Jordan becomes a free-agent. | | CF Thomas Garrett becomes a free-agent. | | 2B Shane Nance becomes a free-agent. | | C Joe Barnard becomes a free-agent. | | MR Ramón Liendo received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Tim Cain received a 1-year contract through automatic renewal worth a total of $400,000. | | 2B Terrance Johnson received a 1-year contract through automatic renewal worth a total of $400,000. | | 2B José Blanco received a 1-year contract through automatic renewal worth a total of $400,000. |
| Thursday, November 25th, 2021 | | SP Justin Thompson received a 1-year contract through arbitration worth a total of $900,000. | | CF Ray Long received a 1-year contract through arbitration worth a total of $7,500,500. | | CL Ron Orr received a 1-year contract through arbitration worth a total of $7,500,000. | | SS Dean Aldridge received a 1-year contract through arbitration worth a total of $1,420,000. | | MR Billy O'Neal received a 1-year contract through arbitration worth a total of $2,187,000. | | SP William Douglas received a 1-year contract through arbitration worth a total of $2,800,000. | | RF Freddie Young received a 1-year contract through arbitration worth a total of $6,126,000. | | LF Tom Dares received a 1-year contract through arbitration worth a total of $1,650,000. | | RF Héctor Mendoza received a 1-year contract through arbitration worth a total of $1,050,000. | | MR Jake Bailey received a 1-year contract through arbitration worth a total of $600,000. | | 1B Tony Hudson received a 1-year contract through arbitration worth a total of $1,020,000. |
| Friday, November 5th, 2021 | | Signed SP Oki Okada to a 5-year contract extension worth a total of $65,500,000. |
| Tuesday, September 7th, 2021 | | Placed CF Thomas Garrett on the active roster. |
| Monday, August 30th, 2021 | | CF Thomas Garrett was designated for assignment and placed on waivers. | | Placed RF Freddie Young on the active roster. | | Activated RF Freddie Young from the 60-day disabled list. |
| Saturday, July 24th, 2021 | | Signed MR Jason Lambert to a 2-year contract extension worth a total of $13,820,000. |
| Thursday, July 22nd, 2021 | | Signed RF Travis Wright to a 4-year contract extension worth a total of $79,600,000. |
| Saturday, July 17th, 2021 | | Signed Tim Lewis to a minor league contract with a signing bonus of $980,000. |
| Friday, July 16th, 2021 | | Signed Eduardo Rivera to a minor league contract with a signing bonus of $910,000. |
| Thursday, July 15th, 2021 | | Signed Terrance Johnson to a minor league contract with a signing bonus of $1,310,000. | | Signed Harry Gillingham to a minor league contract with a signing bonus of $190,000. |
| Sunday, July 11th, 2021 | | Signed John Turner to a minor league contract with a signing bonus of $180,000. |
| Saturday, July 10th, 2021 | | Signed Jay Brown to a minor league contract with a signing bonus of $260,000. |
| Wednesday, July 7th, 2021 | | Signed Hugo Ávila to a minor league contract with a signing bonus of $1,700,000. |
| Tuesday, May 25th, 2021 | | Signed free agent CF Thomas Garrett to a 1-year contract worth a total of $500,000. |
| Thursday, April 1st, 2021 | | Signed SP William Jordan to a 1-year contract extension worth a total of $400,000. |
| Saturday, February 6th, 2021 | | Signed free agent MR Daniel Lutz to a 2-year contract worth a total of $16,800,000. | | Signed free agent SP Ryan Mays to a 2-year contract worth a total of $14,580,000. |
| Friday, February 5th, 2021 | | Signed free agent MR Vance McElroy to a 2-year contract worth a total of $5,660,000. |
| Sunday, November 29th, 2020 | | SP Oki Okada received a 1-year contract through automatic renewal worth a total of $410,000. | | SP Justin Thompson received a 1-year contract through automatic renewal worth a total of $410,000. | | MR Brit Frost received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Dean Aldridge received a 1-year contract through automatic renewal worth a total of $410,000. | | MR Daniel Lutz becomes a free-agent. | | SP Ashton Austin becomes a free-agent. | | MR Billy O'Neal received a 1-year contract through automatic renewal worth a total of $410,000. | | LF Tom Dares received a 1-year contract through automatic renewal worth a total of $400,000. | | MR Ramón Liendo received a 1-year contract through automatic renewal worth a total of $400,000. | | MR David Butler received a 1-year contract through automatic renewal worth a total of $400,000. | | 3B Curtis Downing received a 1-year contract through automatic renewal worth a total of $400,000. | | SS Ray Miller received a 1-year contract through automatic renewal worth a total of $400,000. |
| Thursday, November 26th, 2020 | | CF Ray Long received a 1-year contract through arbitration worth a total of $7,500,500. | | CL Ron Orr received a 1-year contract through arbitration worth a total of $7,000,000. | | C Rolland Minor received a 1-year contract through arbitration worth a total of $12,500,000. | | RF Héctor Mendoza received a 1-year contract through arbitration worth a total of $1,000,000. | | MR Jake Bailey received a 1-year contract through arbitration worth a total of $600,000. | | 1B Tony Hudson received a 1-year contract through arbitration worth a total of $1,020,000. |
| Thursday, November 5th, 2020 | | Placed 2B Shane Nance on the active roster. | | Activated 2B Shane Nance from the disabled list. |
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