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| Center Fielders Career Strikeouts Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Strikeouts | PA | Years | Single Season Leaderboard |
| 1. | John Strasser | 790 | 3483 | 2009-2014 | |
| 2. | Walker McElfresh | 747 | 4143 | 2009-2014 | |
| 3. | Jaime Armas | 719 | 3360 | 2009-2014 | |
| 4. | Matthew Shaner | 629 | 3341 | 2009-2014 | |
| 5. | Jacob Northcutt | 598 | 3402 | 2009-2014 | |
| 6. | James Jenning | 536 | 3864 | 2009-2014 | |
| 7. | Santiago Hernandez | 533 | 2833 | 2010-2014 | |
| 8. | James Mahaffey | 527 | 4070 | 2009-2014 | |
| 9. | James Randell | 506 | 3182 | 2009-2014 | |
| 10. | Raul Delao | 503 | 2698 | 2009-2014 | |
| 11. | Luther Eugene | 484 | 2645 | 2009-2014 | |
| 12. | Tyrone Grimshaw | 480 | 2126 | 2009-2013 | |
| 13. | Kenneth Platt | 459 | 2519 | 2009-2012 | |
| 14. | Wilfredo Gonzalez | 428 | 2608 | 2009-2012 | |
| 15. | Robt Wedge | 426 | 2449 | 2009-2012 | |
| 16. | Stephen Foster | 407 | 1771 | 2009-2012 | |
| 17. | William Oney | 373 | 2597 | 2009-2014 | |
| 18. | Anthony Handley | 364 | 1988 | 2011-2014 | |
| 19. | Isidro Ramirez | 362 | 1899 | 2009-2013 | |
| 20. | James Seto | 334 | 1863 | 2009-2012 | |
| 21. | Russell Folk | 333 | 1510 | 2010-2014 | |
| 22. | Robert Christenson | 332 | 2492 | 2009-2014 | |
| 23. | Bill Bonar | 328 | 1589 | 2011-2014 | |
| 24. | John Lopez | 311 | 1760 | 2010-2014 | |
| 25. | Manuel Albo | 298 | 1233 | 2009-2013 | |
| 26. | Willard Gilmore | 294 | 1697 | 2009-2014 | |
| 27. | Robert Barnhouse | 288 | 1743 | 2011-2014 | |
| 28. | Erwin Basabe | 283 | 1618 | 2012-2014 | |
| 29. | Lawrence Nilsen | 280 | 2010 | 2011-2014 | |
| 30. | Jose Tavarez | 278 | 1632 | 2009-2011 | |
| 31. | James Hause | 277 | 1459 | 2010-2014 | |
| 32. | Adrian Espinosa | 273 | 1163 | 2009-2011 | |
| 33. | Leslie Garwood | 267 | 1461 | 2009-2012 | |
| 34. | Robert Wedge | 247 | 1262 | 2013-2014 | |
| 35. | Roland Tostado | 242 | 1279 | 2009-2014 | |
| 36. | Javier Hernandez | 237 | 1044 | 2009-2012 | |
| 37. | Daniel Morgan | 206 | 1008 | 2009-2010 | |
| 38. | Ramon Braza | 186 | 952 | 2009-2013 | |
| 39. | Richard Tozier | 141 | 682 | 2012-2014 | |
| 40. | Matthew Waltman | 136 | 740 | 2009-2011 | |
| 41. | Arturo Antunez | 127 | 476 | 2009-2010 | |
| 42. | Christopher Woolsey | 124 | 1231 | 2013-2014 | |
| 43. | Walter Scott | 119 | 424 | 2009-2013 | |
| 44. | Haseo Tameyoshi | 107 | 566 | 2012-2013 | |
| 45. | Bernardo Fontanals | 102 | 638 | 2009-2011 | |
| 46. | Juan Martinez | 100 | 693 | 2013-2014 | |
| 47. | Terrance Gwynn | 93 | 679 | 2013-2014 | |
| 48. | Sukihiko Miyoko | 85 | 439 | 2009-2010 | |
| 49. | Steven Hermosillo | 74 | 457 | 2012-2014 | |
| Casimiro Sequeira | 74 | 343 | 2009-2009 | ||
| 51. | Valentin Guido | 66 | 228 | 2009-2009 | |
| 52. | Cristian Ramos | 64 | 380 | 2009-2009 | |
| 53. | Leo Acuņa | 61 | 209 | 2009-2010 | |
| 54. | Hugo Latta | 60 | 307 | 2014-2014 | |
| 55. | Armando Ejea | 59 | 268 | 2013-2014 | |
| 56. | Dan Carver | 58 | 326 | 2010-2014 | |
| 57. | Pedro Granados | 57 | 268 | 2009-2009 | |
| 58. | Stephen Dekker | 50 | 338 | 2014-2014 | |
| 59. | Victor Gatton | 45 | 162 | 2009-2009 | |
| 60. | Anibal Sequeira | 41 | 225 | 2009-2010 | |
| Ricardo Torres | 41 | 157 | 2009-2009 | ||
| 62. | Gerald Montero | 39 | 192 | 2009-2009 | |
| 63. | Carlos Faura | 37 | 318 | 2014-2014 | |
| 64. | Jose Perras | 33 | 121 | 2012-2014 | |
| 65. | Ramiro Palermo | 29 | 100 | 2009-2009 | |
| 66. | Michael Kerry | 25 | 174 | 2014-2014 | |
| 67. | Carson Smith | 24 | 207 | 2014-2014 | |
| 68. | Gary Bogart | 19 | 78 | 2009-2009 | |
| 69. | Joel Criado | 18 | 131 | 2011-2011 | |
| 70. | Michael Johnson | 16 | 77 | 2014-2014 | |
| 71. | David Volpe | 14 | 56 | 2009-2009 | |
| 72. | Pruden Cueva | 13 | 64 | 2009-2009 | |
| 73. | Daniel Lundquist | 10 | 41 | 2014-2014 | |
| 74. | Benjamin Cresswell | 9 | 34 | 2014-2014 |
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